British journal of pharmacology, 167(3), 587598. Modified Citrus Pectin (MCP): When it comes to supplements that reduce the effects of stress, clinically researched modified citrus pectin (MCP) doesnt usually make the list but it should. Along with increasing your overall resilience, MCP blocks galectin-3, the alarm protein that triggers inflammation and causes many of the harmful effects associated with chronic stress. It should be noted that results improved when dose size increased. Healing Sleep: The Art and Science of Sleep. It comes from the Magnolia tree famous for its large, dramatic flowers. It was said to treat "fright qi" a condition caused by emotional distress due to fear and anxiety.. It can even change the way your body manages stress, making it much harder to break the stress cycle. It is also commonly used to support gastrointestinal health. Getting adequate amounts of deep sleep is key for mental and physical health. The researchers found that the isoflavones effectively lessened the severity of classic menopausal symptoms, including hot flashes, while magnolia bark eased the participants anxiety. Science. The goal is to eliminate the disease and simultaneously restore health, and in my decades of research and working with patients, Ive seen many outcomes that other doctors would call miraculous. We call it simply, integrative medicine. Nature: Spending time outdoors in nature helps your body and mind relax. In fact, eye-opening research shows a direct link between galectin-3 and depression, making this alarm protein a strong potential target in treating stress-related mental illness. As you practice meditation over time, youll notice how much clearer and calmer your mind and emotions become. The magnolia extract improved health issues such as anxiety, insomnia, depression, and libido. I recently got some mulungu extract which I heard is the ultimate anxiety reducer but still waiting to try it because even taking a new supplement is anxiety inducing haha. 2005 - 2023 WebMD LLC, an Internet Brands company. Z., Luo, Y. J., Huang, Z. L., Urade, Y., & Qu, W. M. (2012). A study in mice found a magnolol dose of 2.30.9 mg per pound (525 mg per kg) of body weight significantly decreased sleep latency, or the amount of time it takes to fall asleep (27). If cancer is smart, we have to be brilliant and with leading-edge integrative strategies, we can be. Our website content is for informational purposes only. In this article, we will look at the health benefits of magnolia bark, its safety, and its history. The buildup of fat around the liver is among the major causes of liver failure due to various reasons. Consider alternative sleep herbs that are harvested in a more sustainable manner. The bark, leaves, and flowers of the houpo magnolia tree are used in traditional medicine to treat anxiety, depression, and more. Exercise also helps regulate your bodys stress responses so you become less reactive when faced with stressors. https://doi.org/10.3390/ijms16047493. Further, in traditional Chinese medicine, the bark was used for the stomach, large intestines, and lungs. Safety Class: 2b (Not to be used during pregnancy). Dr. Low Dog noted that an earlier study from Italy found that magnolia bark extract combined with magnesium improved sleep, mood, depression and anxiety in menopausal women. Some chemicals in phellodendron might reduce redness and swelling. Magnolia bark has been used for centuries to treat digestive problems, including nausea, abdominal pain and bloating, diarrhea, and loss of appetite. Meditation: If youve never tried meditation before, you might feel like youre doing it wrong but there is no wrong here. Youre Not Alone, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Thats because chronic stress keeps the brain flooded with high levels of cortisol the stress hormone and that can interfere with optimal brain function. Although there isnt much historical information on the magnolia tree and magnolia bark in Asia, there were sightings of the tree in North Carolina as early as the 16th century. As always, make sure to consult your doctor before making any changes to your diet or adding a new supplement. Chilampalli, S., Zhang, X., Fahmy, H., Kaushik, R. S., Zeman, D., Hildreth, M. B., & Dwivedi, C. (2010). Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Retrieved from: https://www.christopherhobbs.com/webdocs/class-handouts/various/Healing-Sleep-Breitenbush.pdf, Hu, J., Chen, L. J., Liu, L., Chen, X., Chen, P. L., Yang, G., Hou, W. L., Tang, M. H., Zhang, F., Wang, X. H., Zhao, X., & Wei, Y. Q. The supplement has been used in traditional Chinese medicine for thousands of years, and current research has confirmed that magnolia bark has many potential benefits for humans. An animal study utilizing Magnolia officinalis bark extract proved to reduce anxiety while having a neuroprotective effect. See additional information. Researchers reviewed studies of pine pollen, and one study reported side effects of diarrhea, bloating, and loss of appetite. He needed to be stabilized, and then an impossible rehabilitation awaited. The genus of the tree was named after the French physician, Pierre Magnol, who was a well-regarded botanist in the 17th century. When the danger passes, the system turns off and resets. Moreover, oxidative stress is widely believed to contribute to diabetes and its related complications. Since ancient times, herbs have been used as natural remedies for a variety of viral infections. The same study observed that the same dose increased REM (rapid eye movement) and non-REM sleep. The second formula, called Saiboku-To (Japanese) is a formula that is said to reduce asthma symptoms through its anti-inflammatory properties. $7.77 ($0.13/Count) In Stock. So go for a walk, take a bike ride, or dance around the room and let those endorphins kick in. Once it matures, the height can reach up to 100 feet and the canopy can spread at up to 70 feet. Dr. Jeffrey Barke, MD, is a Family Medicine specialist practicing in Newport Beach, CA with 33 years of experience. For mild to moderate depression, I recommend exercise 30 minutes a day. Chemopreventive effects of honokiol on UVB-induced skin cancer development. For digestive problems, magnolia bark. In a sleep study, honokiol was able to shorten the time it took for mice to fall asleep and increased the amount of time spent asleep. When the body perceives itself to be under attack, it produces more galectin-3, which in turn triggers a cascade of inflammatory signals, all of which fuel cancer and chronic diseases. In a trial involving Magnolia officinalis extract (MOE), stomach ulcers in mice were healed after receiving 30-120mg daily of the extract. The combination was tested against an independent honokiol dose and an independent radiation dose. But when you face stressors all the time work deadlines, traffic jams, bad news the system cant turn off. In addition to this, the mice spent more time in deep sleep resulting in an overall higher quality of sleep. Below are the top researched-backed magnolia bark benefits for health. Research shows that both magnolol and honokiol are, by nature: The extract of the magnolia bark has been used for thousands of years in traditional Chinese and Japanese medicine. Anticancer research, 30(3), 777783. When taken together, the evidence conveys that magnolia bark extract may help with the psycho-affective symptoms of menopause. This item: Swanson Magnolia Bark Antioxidant Support 400 Milligrams 60 Capsules. This researched form of MCP has a very specific molecular weight and structure which allows it to enter the circulation from the digestive tract, and bind to the carbohydrate receptors on galectin-3 molecules, safely disarming them. The symptoms associated with this condition mimic closely the westernized definition of "burnout". It takes an enormous toll on your immune system, leaving you more vulnerable to any infection thats going around. This makes sense, as its known that GABA(A) receptor activity is closely associated with sleep (29). Neolignans are a type of polyphenol micronutrient in plants. The bark is harvested from April to June where it is then dried in shade. Currently, there are no official recommendations for magnolia bark dosage. My mission is to provide a holistic approach to health and wellness, and bringing balance to the min In a mouse study, honokiol proved to elicit the anxiolytic effect in Hange-koboku-to and Saiboku-to, two medicines used in traditional Chinese medicine and Kampo (traditional Japanese medicine). (2018). Both the root and branch bark are used in therapeutic medicine. Based on research in mice, some scientists believe that honokiol may help combat aging by increasing antioxidant enzymes and decreasing levels of methane dicarboxylic aldehyde (13). Magnolia bark I tried 5 ish times desperate for it to work and it was a pretty nightmarish experience every time. Excess stress is a common problem. Suma Root: Nutrients, Benefits, Downsides, and More, Sorrel: Nutrients, Benefits, Downsides, and Recipes, 15 Impressive Herbs with Antiviral Activity, Anti-Inflammatory Diet 101: How to Reduce Inflammation Naturally, 13 of the Most Anti-Inflammatory Foods You Can Eat, The Signs and Symptoms of Too Much Stress. Cissus quadrangularis: Uses, Benefits, Side Effects, and Dosage, Galangal Root: Benefits, Uses, and Side Effects. Magnesium supplements can also interact with other drugs and change how they work in your body. Additionally, a test-tube study found that magnolol inhibited the growth of lung cancer cells (21, 22). There are so many ways that chronic stress harms your body, mind, and mood. Balanced bacteria in the gut promotes healthy digestion, as well as improved mental health. Is It (Finally) Time to Stop Calling COVID a Pandemic? In a 2022 study, a supplement containing magnolia bark and phellodendron bark (Phellodendron amurense) was used to reduce stress and cortisol levels in 56 moderately-stressed participants. biloba fruits and their protective effects against free radical-induced oxidative damage. That inflammation reaction is a key way that chronic stress leads to serious mood disorders such as anxiety and depression. Magnolia bark is a popular herb used for gut health and stress-induced anxiety. What Is Elecampane Root, and Does It Have Benefits? What if we could use our minds to reduce galectin-3? The bark of the magnolia tree has been used for thousands of years in both traditional Chinese and Japanese medicine. Its thick bark is used to make medicine. In vitro and animal data. Exclusive Lifestyle, Nutrition & Health Advice. Later, it was described in many famous Chinese medical texts such as the "Jingui Yaolue" and the "Shanghan Lun" (ca. It combines excellent craftsmanship in traditional Chinese wellness therapy: Chinese full body massage, foot massage. Between species, the flowers vary in shape, color, and smell, however, the bark can be interchangeably used in medicine. Galectin-3 allows tumor cells to stick together, develop blood supply, metastasize and evade the immune system. It is also commonly used to support gastrointestinal health. It confuses your immune system so much that it triggers immune overreactions and under-reactions. When we address unhealthy galectin-3 expression with proven methods, we effectively treat not just cancer, but numerous life-threatening conditions as well. The safest way to get magnesium is by eating a diet filled with magnesium-rich foods. As mentioned, magnolia bark extract appears to have protective effects against many neurological conditions. In a 2016 review, magnolia bark was found to improve high blood sugar levels and diabetic complications in animals (15). 4 But in this study, pine pollen was combined with metformin, a drug that can cause those side effects. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Magnolia bark has traditionally been used to treat digestive problems, including abdominal bloating and pain, nausea, diarrhea, and loss of appetite. magnolia bark ( Magnolia officinalis) N-acetylcysteine probiotic ( Lactobacillus helveticus) tribulus ( Tribulus terrestris) This doesn't mean that these supplements won't have the same effects in humans, but it does mean that their effectiveness in humans has not yet been clinically proven. He is founder and medical director ofAmitabha Medical Clinic and Healing Center in Santa Rosa, CA, where he and his team of practitioners pioneer individualized treatments for cancer and chronic illness. are clickable links to medically peer-reviewed studies. We aim . OncoTargets and therapy, 11, 52195226. Scientific research also shows a strong connection between chronic stress and Alzheimers disease. Other powerful herbs found in stress preparations and on their own in tea and/or supplement form are lemon balm, valerian, California poppy, hops, milky oats, St. Johns Wort, skullcap, and . Polyphenols are highly valued for their antioxidant levels and believed to offer many health benefits. It was also valued in TCM for its ability to reduce inflammation, anxiety, and bloating.. Cancer statistics, 2020. Zhang, W. W., Li, Y., Wang, X. Q., Tian, F., Cao, H., Wang, M. W., & Sun, Q. S. (2005). Various studies on honokiol support the use of this polyphenol in magnolia bark as a therapy for cancer treatment and prevention. Magnolia bark is a powerful supplement prepared from the bark, leaves, and flowers of the houpo magnolia tree. Healthy foods, especially fruits and vegetables, packed with nutrients and antioxidant compounds help your body cope with the damaging effects of stress. Lastly, a study in rodents noted that a mixture of honokiol and magnolol caused antidepressant-like effects, including improvements in serotonin levels in the brain and reductions in corticosterone levels in the blood (26). Standard dosing for magnolia bark is as follows: Decoction (tea made from bark or berries): 3 10g per person/day, Dietary Supplement: 200 800mg per person/day, Relora (Magnolia/Phellodendron supplement): 250mg, 3x/day. Our team aims to be not only thorough with its research, but also objective and unbiased. 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