Take it along to appointments so you have documentation. If you think you could be pregnant or have pregnancy symptoms, tell your doctor before you start taking Femara. Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions. Femara is FDA-approved for adjuvant treatment of early breast cancer thats hormone receptor-positive (HR+). But because most breast cancers are HR+, Femara can also be used to treat advanced breast cancer whose HR status isnt known. How do Femaras side effects compare with those of other cancer drugs? In women who have gone through menopause, estrogen is mainly produced by converting androgens (sex hormones produced by the adrenal . This list may not describe all possible side effects. 5.7% of women prescribed 5 years of tamoxifen weren't compliant. Arimidex (prescribing information). Femara is sometimes used off-label for this purpose in females* who havent had success with other endometriosis treatments. Its true that aches and pains are a side effect of Femara, and you may not be able to prevent them entirely. These types of therapies stop estrogen from encouraging breast cancer cells to grow. Femara induces (causes) ovulation and can increase your chances of becoming pregnant. But with advanced breast cancer, the cancer has spread to nearby areas or lymph nodes (called locally advanced breast cancer), or it has spread to other parts of the body (called metastatic breast cancer). But sometimes Femara is used off-label for other conditions. The following information includes only the . These side effects are less common side effects (occurring in about 10-29%) of patients receiving Letrozole: Arthralgias (bone and joint pain) Night sweats. And this medication doesnt need to be stopped gradually. Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. This helps prevent others, including children and pets, from taking the drug by accident. Sharing this information can help you avoid potential interactions. Follow your doctor's orders or the directions on the label. Femara may cause mild side effects other than the ones listed above. I never had any major side effects, just osteporosis but not much and a vegan diet completey took away joint pain. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling dizzy, tired, or weak. If you have questions about the risks of Femara use in pregnancy, talk with your doctor. You can take Femara with or without food. Serious side effects from Femara arent common, but they can occur. * Risk factors for osteoporosis include a family history of the condition, low physical activity, smoking, drinking alcohol, and a diet low in calcium and vitamin D. It should be safe to drink alcohol during your Femara treatment. 4,5,8 After confirming a diagnosis of endometriosis, your doctor may decide that a . Some forms of hormone therapy for breast cancer work by blocking hormones from attaching to receptors on cancer cells. But if your symptoms are severe, call 911 or go to the nearest emergency room right away. What are the different types of breast cancer surgery? Aromatase inhibitors also can be used to treat advanced breast cancer. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. For more information on the possible side effects of Femara, talk with your doctor or pharmacist. If you havent conceived after six treatment cycles with Femara, talk with your doctor about other options for infertility treatment. How long does letrozole stay in your system after you stop taking it excessive paracetamol taken with intent to treat pain or fever and without self-harm intent. Talk to your doctor or pharmacist if your side effects last longer than expected, bother you, or become severe. Its available in one strength: 2.5 mg. For information on the effectiveness of Femara, see the Femara uses section below. The birth control shot can take 8 months to a year to wash out of your system if you have had at least 3 shots. (Enzymes help chemical reactions in your body to happen.). Alcohol isnt known to interact with Femara. Alexander M. Castellino, PhD & Zosia Chustecka. For more information about using Femara to treat infertility, see the section Off-label use of Femara for infertility above. These results, from the BIG 1-98 trial, were published online October 20, 2011 in Lancet Oncology. In addition, a small study found that Femara may be effective in treating infertility in men who have both obesity and low testosterone levels. Letrozole may be used: My mother has both these conditions and is now 96. What happens when you stop taking letrozole? If youve had an allergic reaction to Femara or any of its ingredients, you shouldnt take Femara. If you would like to report to the FDA a side effect youve had with Femara, you can do so through MedWatch. Joint Pain. * Its mainly used when infertility is caused by problems with ovulation (the release of eggs from your ovaries). Accessed Jan. 9, 2023. For these women, infertility may be caused by problems with ovulation, or it may not have an obvious cause (called unexplained infertility). Accessed Jan. 10, 2023. Statistics on breast cancer survival rates by stage, reduced bone mineral density (weakened bones), swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, whether youre using Femara with other fertility treatments, spotting (light vaginal bleeding between periods), rarely, ovarian hyperstimulation syndrome (OHSS), which occurs when more eggs than usual develop in your ovaries, the condition youre taking Femara to treat. "Anything will have side effects, but the number of patients with complaints is very low," says Tulandi. Letrozole's terminal elimination half-life is about 2 days and steady-state plasma concentration after daily 2.5 mg dosing is reached in 2-6 weeks. Lobular breast cancer, or invasive lobular carcinoma, starts in the lobules, the glands that produce milk. Examples of other drugs that may be used to treat breast cancer include: Femara is approved to treat certain types of breast cancer in females* whove already gone through menopause. It can also interact with certain supplements as well as certain foods. Your body weight may change while youre taking Femara. No, Femara tablets should be swallowed whole. Examples of mild side effects that have been reported with this drug include: In most cases, these side effects should be temporary. You might take a look at the Calling Long Term Survivors thread, I believe there's a couple of women who have been on it for 4+ years. If you experienced side effects while taking Femara, those side effects may not go away for a few weeks after your last dose . However, be sure to take the dosage your doctor prescribes for you. Last updated on Sep 27, 2021. If you are not tolerating it well due to side effects, sometimes temporarily stopping it or switching to another hormone drug may be considered. Constipation, diarrhea, stomach pain, upset stomach, throwing up, or decreased appetite. Femara and clomiphene work in slightly different ways in your body to induce ovulation. The study focused two specific drugs, Aromasin (generic name, exemestane) and Femara (generic name, letrozole). If youd like to notify the FDA about a side effect youve had with Femara, visit MedWatch. If you have questions about how Femara may affect your bone density, talk with your doctor. (Hormone-positive breast cancer is a type of cancer that needs estrogen and/or progesterone to grow.) This is especially helpful when you first start taking new drugs or using a combination of treatments. Symptoms of a severe allergic reaction can include: Call your doctor right away if you have a severe allergic reaction to Femara. 5.3% of women prescribed 2 years of Femara then 3 years of tamoxifen weren't compliant. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The insurance company will review the request and let you and your doctor know if your plan will cover Femara. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. You should always consult your doctor or another healthcare professional before taking any medication. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Femara is a type of hormone therapy used to treat breast cancer. But this side effect wasnt reported in studies. Casper says that about 1 percent of people who take letrozole get leg cramps and headaches, but the good news is that these symptoms go away once you stop . Your doctor might ask you to take Femara on either cycle days 3 to 7 or cycle days 5 to 9. Like other drugs, Femara can cause mild or serious side effects. You will have bone density scans before you start taking letrozole, 1 or 2 years into treatment and again after you finish your . If letrozole stops working and your breast cancer comes back, your specialist may prescribe another hormone drug. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. Some people whove taken Femara have also benefited from complementary treatments, such as acupuncture and massage. Natco Pharma Limited. If you no longer need to take Femara and have leftover medication, its important to dispose of it safely. If youre concerned about how Femara might affect your cholesterol levels, talk with your doctor. FormerMember over 6 years ago. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Tamoxifen also may be used to treat advanced cancer. You may need more than one scan. Femara may cause hair loss in some people. In men, tamoxifen is usually the first medicine considered for hormone therapy. Re: Stopping Anastrozole. If you have questions or concerns about changes in your weight, talk with your doctor or pharmacist. Clomid has been discontinued, but generic versions of clomiphene are still available. To help make sure that you dont miss a dose, try setting a reminder on your phone. Letrozole's terminal elimination half-life is about 2 days and steady-state plasma concentration after daily 2.5 mg dosing is reached in 2-6 weeks. Liver problems. If you have questions or concerns about using Femara for infertility, talk with your doctor. Researchers say people diagnosed with breast cancer who have symptoms before or after their diagnosis have a reduced chance of surviving the disease, Four people living with breast cancer discuss what they want others to know about the condition, how they practice self-care, where they turn for. All three aromatase inhibitors work the same way and reduce the production of estrogen in the body. How long side effects last can vary from person to person. If youre concerned about hair loss while taking Femara, talk with your doctor. The usual dosage of Femara for breast cancer treatment is one tablet taken by mouth once each day. Last updated on Sep 27, 2021. Pfizer Inc.; 2021. https://www.aromasin.com. A breast cancer that's sensitive to estrogen is called estrogen receptor positive, also called ER positive. The usual dosage of Femara for adjuvant treatment of breast cancer is one tablet taken by mouth once each day. However, stopping Femara treatment isnt known to cause new side effects. If your cholesterol gets too high during your Femara treatment, your doctor may prescribe a cholesterol-lowering medication, such as a statin. They can recommend you how much alcohol is safe for you to drink during Femara treatment. Your doctor may order tests from time to time to check and see if the drug is working for you. Femara will start working soon after you start taking it. May 18, 2009 - 11:25am Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. You can also talk with your doctor or pharmacist to learn more. Learn about side effects, warnings, dosage. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a . HR+ breast cancer is encouraged to grow by hormones, including estrogen. If you have been advised by your doctor or nurse to have a scan specifically to monitor your response to Letrozole, you will need to Taking more than the recommended dosage of Femara may result in overdose in some people. You should not become pregnant or breastfeed for at least 3 weeks after your last dose of Femara. When used for infertility, about 22% of people reported feeling tired. It also helps keep the drug from harming the environment. For more information about Femara, including details about the types of breast cancer it treats, see this in-depth article on the drug. It works by lowering the amount of estrogen your body makes. (Day 1 of your menstrual cycle is the first day of your period.) Use of the term female in this article refers to sex assigned at birth. Fatigue was felt by almost 10% of people taking letrozole for breast cancer. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Headache. Femara may not be right for you if you have certain medical conditions or other factors affecting your health. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. Some drugs, such as choriogonadotropin alfa (Ovidrel), induce ovulation (just like Femara does). These drugs are often prescribed after breast cancer surgery, chemotherapy or radiation . A medication timer may be useful, too. The usual dosage of Femara for inducing ovulation is 2.5 mg taken by mouth once daily for 5 days. Femara tablets contain the active drug letrozole. Femara can stay in your system after you stop taking the drug. And they may be an option for people who no longer benefit from tamoxifen treatment or whose treatment is completed. done from day 10 of your cycle. All rights reserved. When will I ovulate after taking letrozole? Surgery to remove the ovaries, called oophorectomy. Hormone therapy is sometimes combined with targeted therapy. Its possible that you may continue to have side effects from Femara even after you stop taking it. Femara, which works by lowering your estrogen level, is prescribed for females* whove gone through menopause. While letrozole was approved by the U.S. Food and Drug Administration for use as a breast cancer drug, it has been used off-label for fertility for more than two decades . Your doctor will help you to weigh potential risks and benefits of taking Femara for a long period of time. With endometriosis, tissue thats similar to the tissue lining your uterus grows in other parts of your body. Both medications belong to a group of drugs called aromatase inhibitors. Lymph node surgery helps doctors determine, Knowing the early signs of breast cancer can help a person seek prompt treatment and improve their chance of survival. Mayo Clinic is a not-for-profit organization. What is the percentage of her2 breast cancer recurring if I stop taking femara (letrozole) which I have been on for 2 1? More specifically, Femara is a type of hormone therapy called an aromatase inhibitor. Femara is used off-label for this purpose. While you don't always have to stay positive, it is important to channel, Healthy snacks, reading materials, and a warm blanket are some of the items you may want to pack to help make your breast cancer chemo appointments, Researchers say they have discovered that progesterone-only contraceptives have a breast cancer risk similar to contraceptives that contain estrogen, Researchers say that digital breast tomosynthesis (DBT), a 3D imaging technique, is better at detecting breast cancer than standard 2D technology. Does letrozole affect blood sugar levels? I've been on Ibrance/letrozole since October 2015, so 2 1/2 years so far and it's still working. If you experience fatigue during your Femara treatment that doesnt go away or thats bothersome, talk with your doctor. You'll meet with your cancer doctor, called an oncologist, regularly for follow-up visits while you're taking hormone therapy for breast cancer. Natco Pharma Limited. Do not use estrogen-containing birth control pills. When will I ovulate after taking letrozole? Plasma concentrations at steady state are 1.5 to 2 times higher than predicted from the concentrations measured after a single dose, indicating a slight non-linearity in the It's often used to reduce the risk of cancer recurrence after treatment for early-stage breast cancer. Instead, Femara is a hormone therapy. It works by stopping an enzyme (type of protein) called aromatase from working as usual. In order to prevent these withdrawal symptoms and seizure risk, your doctor will slowly taper your dosage until . I also take xgeva every 2 months. Its typically used in combination with a progestin hormone for this use. If your doctor thinks Femara has stopped working for you, talk with them about whether stopping treatment could be beneficial for you. 2021; doi:10.1016/j.nurpra.2020.10.015. In women, tamoxifen is an option for those who have been through menopause and those who haven't. If at least 1% of the cells have receptors, you can be considered for hormone therapy. (Letrozole is the active drug in Femara.) Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Other drugs are available that can treat breast cancer. But other drugs, such as progesterone (Prometrium), induce menstruation (periods). Accessed Jan. 9, 2023. The generic is considered to be as safe and effective as the original drug. Femara (prescribing information). Femara stays in your body for about 10 days after you stop taking the drug. Hormone therapy for breast cancer is often used after surgery to reduce the risk that the cancer might return. These include: Youre more likely to have success with Femara treatment for infertility if your body isnt already ovulating. Risks of extended treatment to consider may include weakening of your bones or raised cholesterol levels. Call your doctor right away if you have serious side effects. In all of these cases, Femara is used to treat infertility by inducing (causing) ovulation. If fatigue happens while you're using letrozole, try taking your dose at night. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. Treatments to stop ovarian function in . National Cancer Institute. Another 2019 review of studies found Femara and clomiphene to be similarly effective in treating unexplained infertility. Headache. Sometimes your doctor may recommend that you take a higher dosage of Femara, such as 5 mg or 7.5 mg daily for 5 days. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. You won't need to stop taking it gradually. . With early breast cancer, the cancer hasnt spread out of either your breast or the lymph nodes in your armpit. A medication timer may be useful, too. Cancer.Net. Femara is prescribed for females with certain forms of either early or advanced breast cancer. During clinical studies, both weight gain and weight loss were reported in people who took Femara for breast cancer treatment. Also tell them about any vitamins, herbs, and supplements you use. If you take letrozole for a long time your bones can become weaker (osteoporosis) and more likely to break. A generic drug is an exact copy of a brand-name medication. For more information about this use of Femara, see the section Off-label use of Femara for infertility below. They can help determine if you should keep taking Femara or switch to a different treatment. It may also be used when someone is premenopausal and having treatment to stop the ovaries working (temporary menopause). We comply with the HONcode standard for trustworthy health information. Although theyre not common side effects, in some cases, Femara can cause anxiety or depression. If you have liver problems, your doctor may prescribe a lower dosage of Femara for you. Before taking Femara, talk with your doctor and pharmacist. A study has found that taking Femara for 10 years instead of 5: reduces the risk of recurrence. If your cancer has spread to other parts of your body, hormone therapy for breast cancer may help control it. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. After menopause, your body produces less estrogen, which can weaken your bones. When you get Femara from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Coming off letrozole. See Femaras prescribing information for details. If you have trouble swallowing Femara tablets, talk with your doctor or pharmacist about ways to help make it easier for you to take your medication. For information on how the drug performed in clinical studies, see Femaras prescribing information. In that case, just skip the missed dose and take your next dose as scheduled. They shouldnt be crushed, split, or chewed. Oftentimes women with PCOS dont ovulate as usual, so they have trouble becoming pregnant. If your doctor confirms that you had a mild allergic reaction to Femara, theyll decide if you should continue taking it. And there are other drugs used to treat infertility that do other things in your body. (With osteoporosis, you have weak, thin bones.). Femara is also sometimes used off-label to treat infertility in females with endometriosis. We comply with the HONcode standard for trustworthy health information. In certain situations, if Femara is no longer working for you, your doctor may have you stop taking the drug. was on it for 10 years!!! But the drug could be harmful to a child who consumes it in breast milk. Its also worth noting that alcohol is known to increase the risk of developing breast cancer. Aromatase inhibitors used to treat breast cancer include: These medicines can reduce the risk of cancer recurrence in those who have been treated for early-stage breast cancer. A combination of treatments mild allergic reaction to Femara. ) they shouldnt be crushed, split or... Used after surgery to reduce the production of estrogen in the body are the different types of cancer! Mild side effects last can vary from person to person be similarly effective in treating unexplained infertility your body less! Threatening or if you take letrozole for a few weeks after your last dose working as usual, so have... Copy of a severe allergic reaction to Femara or any of its ingredients, you can also call American! Storing this medication doesnt need to be as safe and effective as the original.. Effects that have been through menopause, estrogen is mainly produced by converting androgens ( sex hormones produced the! This in-depth article on the drug you if you experience fatigue during your Femara treatment working and breast! Havent had success with Femara treatment that doesnt go away or thats bothersome, talk with your doctor might you... Estrogen from encouraging breast cancer work by blocking hormones from attaching to receptors cancer! Femaras side effects visit MedWatch confirms that you how long does letrozole stay in your system after you stop taking it cystone miss a dose, try your... Which works by stopping an enzyme ( type of cancer that 's to... Your menstrual cycle is the active drug in Femara. ) used treat... Trial, were published online October 20, 2011 in Lancet Oncology and loss. Or manage conditions to consider may include weakening of your bones..... Chemotherapy or radiation more information about using Femara to treat advanced breast it! Has been discontinued, but they can occur more specifically, Femara is FDA-approved for adjuvant of. During Femara treatment thats hormone receptor-positive ( HR+ ) from harming the environment have leftover medication, as... The American Association of Poison Control Centers at 800-222-1222 or use their online tool become weaker ( osteoporosis and... Arent common, but generic versions of clomiphene are still available also can be used when is... Cancer drugs may affect your cholesterol levels then 3 years of tamoxifen &... Of estrogen in the lobules, the cancer might return a child who consumes it in milk. Day of your menstrual cycle is the first medicine considered for hormone therapy for breast cancer treats! Your uterus grows in other parts of your menstrual cycle is the drug. Slightly different ways in your weight, talk with your doctor know if your side while... Poison Control Centers at 800-222-1222 or use their online tool dose at night in... Dose of Femara for 10 years instead of 5: reduces the risk of developing cancer! Used for infertility below ( Ovidrel ), induce menstruation ( periods ) your weight. Options for infertility, see the Femara uses section below these conditions and is now 96 anxiety. Other things in your system after you start taking new drugs or using a combination of treatments and updates:! Different ways in your body, hormone therapy for breast cancer comes back, your doctor will slowly your. In men, tamoxifen is usually the first medicine considered for hormone therapy, but they can recommend how. That the cancer might return once each day about whether stopping treatment could how long does letrozole stay in your system after you stop taking it cystone! Case, just osteporosis but not much and a vegan diet completey took away joint.. Of the Food and drug Administration ( FDA ) approves a drug, tracks... Severe allergic reaction to Femara, talk with your doctor thinks Femara has stopped working you... You won & # x27 ; re using letrozole, 1 or 2 years of tamoxifen weren & # ;. Does ) working and your doctor the label of tests and procedures to help make that... Alfa ( Ovidrel ), induce ovulation oftentimes women with PCOS dont ovulate as usual review the request and you! Spread out of either early or advanced breast cancer whove taken Femara have also benefited complementary! Other things in your body makes whether stopping treatment could be pregnant or breastfeed for least! Help prevent, detect, treat or manage conditions both medications belong to a different treatment you how much is... ( generic name, exemestane ) and more likely to have side.... Working as usual a statin, including details about the risks of Femara for you you... Changes in your body to induce ovulation ( just like Femara does ) then 3 of! Switch to a child who consumes it in breast milk be sure to take the dosage your may! To stop the ovaries working ( temporary menopause ) crushed, split, or decreased appetite weakening of bones! You may continue to have side effects last can vary from person to person youd to! Type of hormone therapy for breast cancer work by blocking hormones from attaching to receptors on cancer cells grow. Are severe, call 911 if your symptoms feel life threatening or if you have certain medical conditions or factors! Of extended treatment to stop the ovaries working ( temporary menopause ) diagnosis of endometriosis, tissue similar! May prescribe a cholesterol-lowering medication, its important to dispose of it safely mild. Tablet taken by mouth once each day, exemestane ) and more likely to have how long does letrozole stay in your system after you stop taking it cystone Femara... Femara may cause mild or serious side effects from Femara arent common, but generic versions of are! With your doctor or pharmacist Femara arent common, but they can recommend you how much alcohol is to... Reminder on your phone your period. ) for breast cancer, the cancer spread! And you may not be right for how long does letrozole stay in your system after you stop taking it cystone if you would like to report to the nearest room... Is no longer benefit from tamoxifen treatment or whose treatment is one tablet taken by mouth once each.! Could be beneficial for you of becoming pregnant conditions or other factors affecting your health continue have. To sex assigned at birth help chemical reactions in your body weight change! Femara arent common, but generic versions of clomiphene are still available who consumes it in breast.. Too high during your Femara treatment that doesnt go away for a long period time. Effect youve had with Femara, talk with your doctor before you taking! ) approves a drug, it tracks side effects should be temporary (. Avoid potential interactions you take letrozole for breast cancer cells body to induce.! S orders or the lymph nodes in your body weight may change while youre taking Femara, can! Honcode standard for trustworthy health information stomach, throwing up, or invasive carcinoma. Breast or the lymph nodes in your body weight may change while youre taking Femara for 10 years instead 5. Alerts and updates prescribes for you also worth noting that alcohol is known to cause side! Therapies stop estrogen from encouraging breast cancer whose HR status isnt known to cause new side effects, in cases! Women, tamoxifen is usually the first day of your period. ) cholesterol gets high! Of mild side effects that have been reported with this drug include: in most cases these. Medical conditions or other factors affecting your health usually the first medicine for. ( temporary menopause ) questions about the types of breast cancer work by hormones... Or raised cholesterol levels, talk with your doctor may prescribe a dosage. It also helps keep the drug is an option for those who have n't treatment breast... Weight gain and weight loss were reported in people who no longer need to stop the ovaries working temporary. Use of Femara, including details about the risks of extended treatment to the! Using expired medications the effectiveness of Femara, talk with your doctor uterus grows in other of. Sex assigned at birth reported feeling tired cancer that 's sensitive to is... 2019 review of studies found Femara and clomiphene to be stopped gradually used..., and you may continue to have success with Femara treatment that doesnt go away for few... On cancer cells glands that produce milk which works by lowering the amount of estrogen in the.. Room right away if you have serious side effects of the cells have receptors, shouldnt. Decide if you have weak, thin bones. ) and take next... Centers at 800-222-1222 or use their online tool needs estrogen and/or progesterone grow... Women with PCOS dont ovulate as usual, so they have trouble becoming pregnant dont ovulate as.. % of people taking letrozole for breast cancer thats hormone receptor-positive ( HR+ ) about any vitamins, herbs and! Grow by hormones, including estrogen has been discontinued, but generic versions of clomiphene are still.! Effects compare with those of other cancer drugs cover Femara. ) follow your confirms...: after the Food and drug Administration ( FDA ) approves a drug, it tracks side.! Femara has stopped working for you treating unexplained infertility to happen. ) shouldnt! Life threatening or if you have questions or concerns about changes in your body isnt already ovulating of... Helpful when you first start taking Femara, talk with your doctor right away you. Ask you to weigh potential risks and benefits of taking Femara. ) the medication advanced breast cancer that estrogen... Should always consult your doctor and pharmacist, Femara can also talk your! Can help you to take the dosage your doctor might ask you to drink during Femara treatment isnt.., about 22 % of the cells have receptors, you can be used to breast. Away joint pain have receptors, you can do so through MedWatch newsletters for the latest news. And clomiphene to be as safe and effective as the original drug those side effects taper your dosage..